That's because PSA levels can fluctuate up and down -- so a man with a high PSA level may not actually have any prostate problems at all. Stage 1 Many men have very high PSA levels and feel just fine.

In addition to BPH, chronic inflammation of the prostate can also lead to an elevated PSA level. Several conditions can lead to an elevated PSA level, not just prostate cancer. "At age 40, a PSA of 2.5 is the normal limit," says John Milner, MD, a urologist in the Chicago area. As men age, the prostate gets larger. They found that the following PSA values had the best prostate cancer specificity: 1.7 ng/ml for men age 59 and younger; 2.25 ng/ml for men ages 60 to 69; and 3.25 ng/ml for those age 70 and older.

If your PSA levels stay normal, you can switch to once-a-year PSA tests.

The PSA level may differ depending on a man’s age.

3. Prostatitis, an inflammation of the prostate, can affect PSA levels.

In one study, researchers evaluated age-specific PSA cut-off values in 2,225 Austrian men who underwent prostate biopsy because of elevated PSA levels. Age-related BPH combined with prostate cancer The PSA test measures the level of prostate-specific antigen in your blood. An acutely inflamed or infected prostate can increase a man's PSA level to 100 nanograms per millilitre (ng/ml) or higher. One study shows that men with this level of PSA often have prostate cancer.

It has to be … In the men with a PSA velocity of 4.0 ng/mL per year or higher, 13% had cancer on their first biopsy and 13% had prostatitis. Further, make sure you do not have an ejaculation for at least 48 hrs prior to the time of the PSA blood draw. In prostate cancer, more PSA gets into the blood than is normal.

Even without any prostate problems, the PSA level of a man can go up gradually as his age. Low PSA levels also don’t always mean that you don’t have prostate cancer. Anything above 4.0ng/mL is considered “abnormal” or elevated. Based on the PCPT and other research, you have: An 8.8 percent chance of having prostate cancer found on a biopsy if your PSA is 1.0 ng/ml or lower A 17 percent chance if your PSA is 1.1 to 2.0 ng/ml A 23.9 percent chance if your PSA is 2.1 to 3.0 ng/ml Of the two types of PSA present in the blood, free PSA is an indication of benign prostate issues and protein bound PSA is associated with malignant conditions. However, the PSA test was first developed only to monitor men who had a history of prostate cancer. Some men who have prostate cancer do not exhibit elevated PSA levels, and some noncancerous conditions, like a prostate infection or benign enlargement, can cause high PSA levels. For example, blood PSA levels are often increased in men with prostatitis or BPH.

The PSA level itself does not predict whether or not a man will have symptoms or how long he will live.

As men grow older, many are affected by prostatitis, an inflammation of the prostate, or benign prostatic hyperplasia (BPH), a non-cancerous enlargement of the prostate which causes PSA levels to rise. 90% aller symptomatischen, chronischen "Prostatitisfälle" gehören zum "Chronischem Beckenschmerzsyndrom" ("Chronic Pelvic Pain Syndrome" (CPPS)).

Continued What Your PSA Numbers Mean. However, it seems sensible to me to ask for the PSA blood draw before the DRE is done. An elevated level of PSA has been asserted to be highly specific for prostate cancer, although patients with large benign prostate glands and those with bacterial prostatitis may also have slightly elevated levels. Of the two types of PSA present in the blood, free PSA is an indication of benign prostate issues and protein bound PSA is associated with malignant conditions.

In fact, the patient may be experiencing nerve pain resulting from tension in the pelvic floor—but the source of nerve pain can be elusive since the pain may be referred (arises in a different place from where it is felt). DRE does not raise PSA values to any significant level. Prostatitis is often associated with CPPS, even though prostatitis may not be the culprit.

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